Chronic, non-healing wounds represent a significant clinical and economic burden. GCell has been studied extensively in diabetic foot ulcers (DFUs), venous leg ulcers, pressure injuries, and post-surgical wound dehiscence. Growth factors concentrated in GCell preparations — including PDGF, TGF-β, VEGF, and EGF — actively promote angiogenesis, granulation tissue formation, and epithelialization.